Vasyl Babenko
Neurologist, Heart Institute, Ministry of Health of Ukraine, Ukraine
Title: Metabolic syndrome and acute ischemic stroke: predictors of functional outcome
Biography:
Abstract:
INTRODUCTION: The aim of study was to establish predictors of functional outcomes of acute ischemic stroke (IS) in patients with metabolic syndrome(MS). METHODS: 202 patients with MS and clinical manifestations of IS were perfomed. The functional outcome after acuit IS was assessed by the modified Rankin scale: 0-1 point –favorable functional outcome (FFO), 2-6 points–unfavorable outcome (UnFO). RESULTS:After IS, the ratio of patients experiencing FFO comprised 48% and UnFO–52%. Statistically significant (p<0,001) main predictors and clinical indicators of AFO after acute IS in patients with MS: NIHSS scale ≥10 points (relative risk (RR) 3.61; p<0,0001),and Bartel index ≤40 points (RR 2.76; р<0,0001); level Glasgow Coma Scale ≤13 points (RR 3.61; р<0,0001); complex intima-media (RR 2.37; р<0,0001); infarct zone≥25,3cm3(RR 3.09; р<0,0001);level of fasting blood glucose ≥7,6mmol/L (RR 2.4; р<0,006); reduction level of HDL lipoproteins (RR 2.37; р<0,0001);occurrence of atherothrombotic(RR 2.21) and cardioembolic subtype(RR 2.41; р<0,0001); ischemic heart disease(RR 1.69; р<0,045); total number components of MS (RR 1.5; р<0,05). SUMMARY:The most important significant predictors of UnFO after acute IS of patients with MS were definded.